- Excellent Outcomes With Reduced Frequency of Vincristine and Dexamethasone Pulses in Standard-Risk B-Lymphoblastic Leukemia: Results From Children's Oncology Group AALL0932by Anne L. Angiolillo on January 19, 2021 at 6:05 am
- Immunotherapy for Hematologic Malignanciesby Charles Craddock on January 19, 2021 at 6:05 am
- Atrial Fibrillation in Patients Undergoing Allogeneic Hematopoietic Cell Transplantationby Ellen K. Chang on January 19, 2021 at 6:05 am
- Prediction of Outcome in Patients With Chronic Lymphocytic Leukemia Treated With Ibrutinib: Development and Validation of a Four-Factor Prognostic Modelby Inhye E. Ahn on January 19, 2021 at 6:05 am
- Autologous Stem Cell Transplantation in the Management of Relapsed Non-Hodgkin Lymphomaby Alvaro J. Alencar on January 19, 2021 at 6:05 am
- Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)by Scott Kopetz on January 19, 2021 at 6:05 am
- Better Together: Clinical and Genomic Data to Inform Shared Decision Makingby Katherine D. Crew on January 19, 2021 at 6:05 am
- Knucklesby Kathryn E. Hitchcock on January 19, 2021 at 6:05 am
- Neratinib in HER2-Positive Breast Cancer With Brain Metastasesby Tim Johannes Adrianus Dekker on January 19, 2021 at 6:05 am
- Health-Related Quality of Life in Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: Findings From the Phase III MAIA Trialby Aurore Perrot on January 19, 2021 at 6:05 am
- Primary Adrenal Lymphomaby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 14, 2021 at 12:00 am
Figure 1.
- Ewing’s Sarcomaby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 14, 2021 at 12:00 am
In 1920, during a meeting of the New York Pathological Society, James Ewing described an unusual tumor in a 14-year-old girl as a "diffuse endothelioma of bone." The tumor had initially been diagnosed as an osteosarcoma, but its architecture, the morphologic features of its cells, and its marked…
- Distribution of KRASG12C Somatic Mutations across Race, Sex, and Cancer Typeby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 14, 2021 at 12:00 am
To the Editor: Hong et al. (Sept. 24 issue) present results of an early-phase clinical trial of sotorasib, which showed promising clinical benefit. Patients had non–small-cell lung cancer (NSCLC; 46%) or colorectal cancer (33%), and White patients constituted 76% of the cohort. As drugs are being…
- Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infantsby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 7, 2021 at 12:00 am
Transmission of maternal cancer to offspring is extremely rare and is estimated to occur in approximately 1 infant per every 500,000 mothers with cancer, whereas approximately 1 in 1000 live births involves a mother with cancer. Table 1 provides data on 18 previously reported cases. In these cases,…
- Dipeptidyl Peptidase 4 Inhibition for Prophylaxis of Acute Graft-versus-Host Diseaseby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 7, 2021 at 12:00 am
Acute graft-versus-host disease (GVHD) remains a major complication and cause of death after allogeneic hematopoietic stem-cell transplantation (HSCT). With the use of standard prophylaxis regimens that include a calcineurin inhibitor with either methotrexate or sirolimus, grade II to IV acute GVHD…
- The Rapid Rise in Cutaneous Melanoma Diagnosesby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 7, 2021 at 12:00 am
The Covid-19 (coronavirus disease 2019) pandemic effectively stopped cancer screening in the United States. Because the pandemic has also produced severe financial strains both for people and for public budgets, a reassessment of the value of various population-wide screening efforts is warranted…
- Sitagliptin to Prevent Acute Graft-versus-Host Diseaseby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 7, 2021 at 12:00 am
Pharmacologic methods to prevent acute graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HSCT) have long relied on combinations of immunosuppressive medications and antibodies to inhibit or deplete donor T cells that recognize alloantigens in the recipient. In…
- Race and Genetic Ancestry in Medicine — A Time for Reckoning with Racismby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on January 6, 2021 at 12:00 am
In the United States, race, ancestry, genetics, and medicine are inextricably linked in a complex and fraught history. Medicine is replete with examples of racial injustice inflicted by the use of race and ethnicity as biologic constructs to engender hierarchical discrimination. Race and ethnicity…
- Acquired Hypertrichosis Lanuginosaby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on December 31, 2020 at 12:00 am
Figure 1.
- Hiding in Plain Sight — Somatic Mutation in Human Diseaseby (The New England Journal of Medicine: Search Results in Hematology\Oncology) on December 31, 2020 at 12:00 am
Beck et al. define an adult-onset inflammatory disorder that unites multiple clinical conditions with previously different diagnoses or with no diagnosis at all; their findings are now reported in the Journal. The VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is defined…